ME6_OA_Neki 1

Background: Non-dipping of nocturnal blood pressure is common in people with type 2 diabetes with hypertension and is associated with increased risk of cardiovascular and renal morbidity and mortality. This study aimed to identify the pattern of nocturnal non-dipping of BP in people with type 2 diabetes and its association with microalbuminuria. Methods: Data was examined from 100 patients with type 2 diabetes with hypertension who had undergone 24hrs ambulatory BP monitoring and it was correlated with urinary ACR, which was done in morning spot urine sample of all the patients. Results: Normal dipping was observed in 45%, non dipping in 46%, extreme dipping in 6% and 3% were reverse dippers in patients having type 2 diabetes and hypertension. It was observed that 24 hr dipping pattern of blood pressure and was strongly related to microalbuminuria (p <0.001). Non dippers were significantly older (p<0.05) with a higher prevalence of albuminuria (p<0.001) as compared to dippers. Nocturnal dipping and albuminuria was found significantly associated with glycemic control, duration of diabetes and hypertension. Conclusion: Non-dipping of nocturnal BP in people with type2 diabetes mellitus and hypertension is strongly associated with microalbuminuria.